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The emerging role of mass spectrometry-based proteomics in drug discovery | Nature Reviews Drug Discovery
A unified drug–target interaction prediction framework based on knowledge graph and recommendation system | Nature Communications
Strategies and challenges for the next generation of antibody–drug conjugates | Nature Reviews Drug Discovery
Evaluating drug targets through human loss-of-function genetic variation | Nature
Design of protein-binding proteins from the target structure alone | Nature
A rational blueprint for the design of chemically-controlled protein switches | Nature Communications
Proteome-wide covalent ligand discovery in native biological systems | Nature
Improving Drug Candidates by Design: A Focus on Physicochemical Properties As a Means of Improving Compound Disposition and Safety | Chemical Research in Toxicology
Automating drug discovery | Nature Reviews Drug Discovery
Avidity in antibody effector functions and biotherapeutic drug design | Nature Reviews Drug Discovery
Engineering precision nanoparticles for drug delivery | Nature Reviews Drug Discovery
Exploring protein hotspots by optimized fragment pharmacophores | Nature Communications
Predictive validity in drug discovery: what it is, why it matters and how to improve it | Nature Reviews Drug Discovery
Immune targets for therapeutic development in depression: towards precision medicine | Nature Reviews Drug Discovery
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Counting on natural products for drug design | Nature Chemistry
A machine learning-based chemoproteomic approach to identify drug targets and binding sites in complex proteomes | Nature Communications
Massively parallel de novo protein design for targeted therapeutics | Nature
Pharmacophore hybridisation and nanoscale assembly to discover self-delivering lysosomotropic new-chemical entities for cancer therapy | Nature Communications
Programmable self-regulated molecular buffers for precise sustained drug delivery | Nature Communications
Targeting cancer metabolism in the era of precision oncology | Nature Reviews Drug Discovery
Bioorthogonal in situ assembly of nanomedicines as drug depots for extracellular drug delivery | Nature Communications
Modulating biomolecular condensates: a novel approach to drug discovery | Nature Reviews Drug Discovery
Advances in covalent drug discovery | Nature Reviews Drug Discovery
New strategy for drug discovery by large-scale association analysis of molecular networks of different species | Scientific Reports
